Pontifical Catholic University of Peru, Peru
Title: Integrative computational pathology and beyond
Biography: Daniel Racoceanu
Histopathology examination represents a milestone of the diagnostic and therapeutic decision. Concretized by the pathology report, essential to the multidisciplinary team (MDT) meetings in hospitals. It relies on professional observation and judgment, integrating: morphological criteria (tumor morphological identity) issued from standard and complementary (histochemistry, enzymology, hybridation in situ, scores) preparations’ observations, consolidated by clinical, radiological and biological contexts - among which, molecular. The future of histopathology is obviously digital (data and images). The challenge is to conciliate, in the framework of the healthcare, various usual missions as: doing the diagnosis for the patient in the present moment, warehousing the medical data for the patient record, and also feeding and structuring the research strategy - particularly in oncology. Due to it's important legal role, the pathology has a key position in the medical diagnostic. At the junction of medical imaging modalities and the omics, this medical exam represents the bottleneck enabling us to go to building a representative local database. We are initiating a program of care monitoring for which the milestones and the impact will be: the production of digital histopathology tools, the modeling of the pathway and the conceptualization of the associated massive database in Peru, with a strong wish to extend it to Andean and Latin American countries. This initiative will allow us to bring in and structure a database (whole slide images, omics, clinical data and metadata) corresponding to a very diverse population (mestizos, amerindians, european, asian-peruvian, afro-peruvians ...) coming from very different regions (coast, rainforest, highlands), with difficult access and difficult to reach, representative to Peru/Andean/Latin American regions.